Is there an objective way for clinics to assess the perimenopause transition?

MARKABLE reads five wellness signals from a selfie and a 7-minute smartphone check (facial biomarkers, cognition, hearing, vision and symptoms) and fuses them into one structured, provider-ready wellness picture that a woman and her clinician can track over time. It is a general wellness product, not a diagnostic test.

How can clinics track the perimenopause transition between visits?

A patient completes a 7-minute check at home each month. The clinic receives a structured, longitudinal wellness summary before the visit, so history-taking is already handled and the visit goes straight to care. No new hardware and no workflow change.

Does MARKABLE change how a clinic treats?

No. MARKABLE sits underneath the care model as an objective data layer. It does not diagnose, does not prescribe, and does not replace clinical judgment, supplements, skincare or the care plan. It gives the clinician an objective starting point and an honest trend. The treatment stays with the clinic.

Is MARKABLE a medical device or a reimbursable service?

No. MARKABLE is a general wellness product for personal awareness and self-monitoring, in line with FDA, MHRA and Israeli MOH general-wellness guidance. It is not a medical device, not a reimbursable service, and not remote patient monitoring. It does not diagnose, treat, cure or prevent any disease.

How does facial analysis relate to hormonal change?

Using a standard smartphone camera, MARKABLE analyzes a broad set of facial parameters across the eye region, facial structure, cutaneous texture, tone and the hairline. These patterns are associated with hormonal change and accumulate over weeks, offering trend data rather than a single point-in-time reading.

Perimenopause Assessment for Clinics

The problem you already see

Perimenopause is volatility. It surfaces across skin, cognition, the senses and dozens of symptoms, and it shifts week to week.

MARKABLE turns that into an objective signal your clinicians can get ahead of, from the phone she already carries.

What the woman experiences

Seven minutes on her own phone, before she ever sees you.

She gets a link from your care team, completes the read at home, and walks in prepared. The same experience works from a waiting room, a living room, or before a telehealth call.

01

An invitation

A text or email from your care team invites her to map where she stands, before the visit.

02

The seven-minute read

A selfie reads facial patterns associated with the hormonal transition, alongside a structured symptom and function check.

03

Her wellness profile

Her signals fuse into one personal profile she can see and understand, in the language of awareness.

04

Ready for the visit

Her profile reaches her clinician ahead of time. She arrives feeling seen, and the visit starts where it matters.

Open the interactive journey →

What your clinician sees

An objective baseline, the trend since last visit, and a summary ready for your chart.

The chart summary, first

A structured intake summary lands at the top of the profile, ready to review and drop into the chart. The clinical note stays yours.

A structured intake, before the visit

Skin, cognition, the senses and symptoms, captured and organized so the visit opens straight on care.

The trend since last visit

Each re-map shows which way her signals are moving, cognitive and physiological, so a follow-up starts from what has changed.

Maya R. · Age 45
Visit 3 · Feb 15, 2026

Structured intake summary · you review & approveCopy to chart

Subjective: Visit 3. On transdermal estradiol 0.05 mg + micronized progesterone 200 mg. Primary focus: worsening sleep onset, recurring urinary discomfort, persistent cold spells (8/10).
Objective (MARKABLE): Cognitive, reaction time improved 0.18s, recall +11%. Physiological, skin hydration +14%, redness -11%. Signals since last visit: cognitive and dermal trending up; sleep and thermoregulation clusters remain elevated.

Current therapy (patient-reported)

Transdermal estradiol 0.05 mg/day, micronized progesterone 200 mg. Started Dec 20, 2025. Adherence: 2 missed doses this cycle. Supplement: magnesium glycinate.

Symptom landscape

Cold spells8/10

Sleep onset difficulty7/10

Urinary discomfort7/10

Changes since last visit

Cognitive

Reaction timeImproved 0.18s

Short-term recallImproved 11%

Digit recallStable

Physiological (visual)

Skin hydrationImproved 14%

Periorbital fine linesDecreased 8%

Facial rednessDecreased 11%

Summarizes patient-reported and observed wellness data. Supports the visit. Not medical advice or a clinical diagnosis.

What it does for your practice

More care in the visit. More reason she comes back.

Straight to care

The visit opens on treatment, not on fifteen minutes of history-taking.

Time back

The intake is already done, so your time goes to judgment, titration and the plan.

Patients who return

She watches her own trend between visits, a reason to keep her follow-ups.

A premium offering

Runs in your name, a differentiated service you include, or price as a premium tier.

Why it fits the way you already work

One layer. At scale, or in a single practice.

MARKABLE sits underneath your care model. It does not change how you treat. It changes how much you know when you do.

For virtual care at scale

It slots into short visits.

The intake is done before the call. The read is complete before she joins, so a 15-minute follow-up opens straight on the care plan.
The trend is visible between visits. Each re-map shows which way her signals are moving, so a follow-up starts from what changed.
Care rests on a trend, not a moment. Every check adds to an objective longitudinal record of her transition, so decisions rest on direction over time.
It is the accessible front door. An early, simple wellness signal that fits alongside the bone, cardiac and metabolic care your clinicians already provide.

For a clinic or practice

It slots into the appointment you already run.

She arrives mapped. The intake is already done, so your time goes to judgment, titration and the plan.
It carries your brand. The whole experience runs in your name, co-branded or fully your own.
She can see her own trend. Between visits she watches her signals move, a reason to keep her follow-ups.
You offer it your way. Include it in your program, or as a premium tier.

How it slots in

It follows the journey you already run.

Referral

She enters your care model exactly as she does today.

Pre-visit read

Seven minutes on her phone, before the first visit.

The visit

Your clinician opens on the profile and builds the plan.

Between visits

Re-mapping and tracking gather the trend.

Follow-up

She re-maps. Your clinician sees how her signals have moved.

Between visits

The habit she keeps is what feeds the next visit.

Between visits she keeps a small, curated set of evidence-based wellness practices, grounded in the menopause and behavioral-health literature and chosen because each one also generates objective data for the visit. Nothing that overlaps with the care, supplements or products you already provide.

Built to complement your care. MARKABLE does not diagnose, does not prescribe, and does not replace your clinical judgment, your supplements, your skincare, or your care plan. It gives your clinician an objective starting point and an honest trend. The treatment stays yours.

The evidence so far

Early, honest, and already live.

0.87AUC, early validationFacial, symptom and cognition model. Internal pilot, N=51. 95% CI 0.72 to 0.97.

5Signal systemsSkin, cognition, hearing, vision, symptoms

7 minOn any phoneNo wearable, no lab, no hardware

LiveProduct todayPatient experience shipping, patent pending

Clinical advisor Eran Gold, MD (OB/GYN) · AI & validation Shachar Fleishman, PhD

Wellness-monitoring pilot in progress with a major Israeli health fund (2M+ members).

Give every midlife visit a head start.

Start with a free pilot, three patients and one real report, no commercial commitment. Then let us show you the clinician side end to end.

Book a walkthrough → Walk the patient journey