The perimenopause data layer

Objective data for the perimenopause transition.

MARKABLE is a non-invasive perimenopause wellness platform. From a selfie and a seven-minute check, it reads a rich set of facial signals, across the eye region, facial structure, skin and hairline, alongside cognition, hearing, vision and symptoms, and fuses them into one structured, provider-ready picture. For clinics, care teams, employers and health plans.

A general wellness product, not a medical device.

See a sample report → Book a 15-min walkthrough

Here for yourself? Try a free personal check →

Periorbital geometry

Brow & hairline density

Cutaneous micro-texture

Facial contour & volume

Chromatic tone mapping

Reading the facial signal layer

I run a clinic or practice

Give every visit a full, structured picture before it starts, and every patient a reason to come back.

For clinics & care teams →

I lead benefits or HR

A private, high-value wellness benefit for the experienced women you can least afford to lose.

For employers →

I manage a health plan

Non-invasive, smartphone-based wellness engagement that reaches every member, at home.

For health plans →

The gap MARKABLE closes

About half of women stop hormone therapy in the first year.³

Often before they feel the benefit. MARKABLE gives the care team an objective, repeatable signal between visits, so support and titration happen on fresh data, month to month.

It does not diagnose, prescribe or deliver care. It is the objective data layer that makes the clinician's work sharper.

Why it works

Five signals. One picture of the transition.

Hormones swing too fast to catch in a single reading. MARKABLE reads the pattern they leave across five body signals and fuses them into one longitudinal, provider-ready picture.

The pattern, read week over week.

Facial and functional signals accumulate over weeks into one longitudinal wellness picture the care team can follow over time, alongside any clinical testing she already has.

Five independent signals, fused into one read.

Facial biomarkers, cognition, hearing, vision and symptoms are read together and fused into a single wellness score, so no single input carries the read on its own.

Non-invasive means repeatable.

From the phone she already owns, at home, in seven minutes. Monthly monitoring happens without a lab visit, a blood draw, or a day off work.

She arrives already in the picture.

Her structured, longitudinal wellness summary reaches the clinician before the visit. The visit is spent deciding, not reconstructing.

For clinics & care teams

Every visit starts ahead. Every patient has a reason to come back.

Your patient completes a seven-minute check at home, and her full picture reaches you before she sits down: the symptoms she downplays, her cognitive and sensory signals, and how her body has moved since her last visit. History-taking is already handled, so the visit goes straight to care, and it runs on the phone she owns and the inbox you already check.

~7 minher check, done
at home

15+ minof history-taking,
already handled

70+symptom domains
surfaced

Start a free pilot → Book a 15-min walkthrough

Provider report

Patient D.R.|Age 45|Visit 3|Jun 7, 2026

Current therapy (patient-reported)

Transdermal estradiol 0.05 mg and micronized progesterone 200 mg, daily. Started under a month ago. Adherence: very consistent. Side effect: spotting.

Visit focus

Hot flashes

Symptom landscape

Sugar cravings9

Headaches / migraines9

Early awakening8

Word retrieval delay6

Bleeding pattern

Last 3 months: more irregular than usual, heavier bleeding.

Functional signals

Cognitive: processing speed, word retrieval, working memory, delayed recall (wellness scores).
Facial (self-check): skin dryness 70 (+2), periorbital fine lines 69 (+5), facial redness 74 (+1) vs last check.

Summarizes patient-reported and observed wellness data. Supports the visit. Not medical advice or a clinical diagnosis.

A benefit that runs itself

No integration needed

Employees self-enroll through a private link. No IT, no API, no platform dependency.

Private by design

The employer sees only aggregate, de-identified engagement, never individual data, except as required by law.

Live in days

Add it to your benefits menu in days, no IT project required.

For employers & benefits leaders

Keep the women who run your business.

Symptoms in the perimenopause transition are quietly pushing experienced women toward the door. MARKABLE gives every woman on your team a private read she does on her own phone, and a credible path back to feeling like herself. It goes live on your benefits menu in days and runs entirely on its own.

$1.8Ba year in lost US
work time⁴

13.4%report an adverse
work outcome⁴

Daysto launch,
zero IT

See the employer view → Book a benefits call

For health plans & insurers

Support members through the transition, at population scale.

MARKABLE helps members notice and self-monitor perimenopause-related wellness patterns from their own phone, and prepare for conversations with their own clinician. It reaches members far from a clinic, with no lab visit and no pre-authorization. The health-equity story your plan can stand behind.

~80%experience vasomotor
symptoms¹

~5%of postmenopausal women
on hormone therapy²

Any phonereaches every
member, at home

See the plan view → Book a plan call

Barriers MARKABLE removes

Lab visitNot required

Pre-authorizationNot required

TransportationNot required

Time off workNot required

Smartphone-based. Scalable. Equitable.

The technology

Five data channels, one wellness profile.

Here is what each of the five signals reads, and why it belongs in the picture.

Facial biomarkers

A single selfie reads a rich set of markers across the eye region, facial structure and volume, cutaneous texture, tone and the hairline, the morphological signals associated with the hormonal transition.

Facial

Cognition

Short on-phone games read processing speed, word retrieval, working memory and recall, the cognitive domains sensitive to hormonal change.

Cognitive

Hearing

Sound tasks read auditory processing, one of the sensory systems that shifts across the transition.

Sensory

Vision

Contrast and color tasks read visual processing, a second independent sensory signal.

Sensory

Symptoms

70+ symptom domains, captured structured, surface the patterns a woman rarely reports on her own.

Self-report

Research & validation

Built on real data, from real women.

In our pilot, the fused model reached an AUC of 0.87. It is early and observational, and we say so plainly. The current model fuses facial, symptom and cognitive signals across more than seventy symptom domains, and the research grows with every check. A paper is in preparation for peer review, and full validation detail is available on request.

0.87AUC, early
observational pilot

5independent wellness
signals fused

70+symptom
domains mapped

~7 mincheck, from
her own phone

Wellness-monitoring pilot in progress with a major Israeli health fund (2M+ members).

Clinical advisor Eran Gold, MD (OB/GYN) · AI & validation Shachar Fleishman, PhD

Encrypted in transit & at rest

Healthcare-grade security & access controls

Designed for GDPR alignment

Patent Pending technology

No photos stored without consent

General wellness product, not a medical device

Questions

Frequently asked questions

Is there an objective way to assess the perimenopause transition? +

MARKABLE reads five wellness signals from a selfie and a seven-minute smartphone check (facial biomarkers, cognition, hearing, vision and symptoms) and fuses them into one structured, provider-ready wellness picture a woman and her clinician can track over time. It is a general wellness product, not a diagnostic test.

How can clinics track the transition between visits? +

The patient completes a seven-minute check at home each month. The clinic receives a structured, longitudinal wellness summary before the visit, so history-taking is already handled and the visit goes straight to care. No new hardware and no workflow change.

Is MARKABLE a medical device? +

No. MARKABLE is a general wellness product for personal awareness and self-monitoring, in line with FDA, MHRA (UK) and Israeli MOH general-wellness guidance. It does not diagnose, treat, cure or prevent any disease.

How does the facial analysis relate to hormonal change? +

Using a standard smartphone camera, MARKABLE analyzes a broad set of facial parameters across the eye region, facial structure, cutaneous texture, tone and the hairline. These patterns are associated with hormonal change and accumulate over weeks, giving trend data rather than a single point-in-time reading.

What does the provider report include? +

A structured summary of the patient's top concerns with severity, symptom clusters across 70+ domains, cognitive and sensory wellness scores, a hormonal wellness trend index, longitudinal trends when multiple checks exist, and suggested discussion points. It supports the visit and is not a diagnosis.

How long does a check take? +

About seven minutes, from the phone she already owns. A selfie, a short set of cognitive games, quick sensory checks and a structured symptom log. Results are available immediately.

Is patient data shared with employers? +

Individual health data belongs to the user. Employers who offer MARKABLE as a benefit receive only aggregate, de-identified engagement metrics, never individual results or health data, except as required by law.

What about photo privacy? +

Facial images are processed and converted into numerical wellness data. The original photo is not stored on our servers unless the user explicitly opts in. All data is encrypted in transit and at rest.

See it work on your own patients.

Book a short walkthrough, or start a free pilot with three patients. Either way, you see a real report before you decide anything.

Book a 15-min walkthrough → See a sample report

Here for yourself? Try a free personal check

References

1. Freeman EW, Sherif K. Prevalence of hot flushes and night sweats around the world: a systematic review. Climacteric 2007;10(3):197-214 (vasomotor symptoms up to ~80%).
2. Yang L, Toriola AT. Menopausal Hormone Therapy Use Among Postmenopausal Women. JAMA Health Forum 2024;5(9):e243128 (4.7% in 2020).
3. Hill DA, Weiss NS, LaCroix AZ. Adherence to postmenopausal hormone therapy during the year after the initial prescription. Am J Obstet Gynecol 2000;182(2):270-276.
4. Faubion SS, Enders F, Hedges MS, et al. Impact of Menopause Symptoms on Women in the Workplace. Mayo Clinic Proceedings 2023;98(6):833-845 (N=4,440; 13.4% reported an adverse work outcome; estimated $1.8B/year US lost work time).